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List of databases contained in the article https://doi.org/10.1590/1678-4685-gmb-2020-0203:

Supplementary tables

Table S1 - Alternative splicing databases

Database URL
AltExtron http://bioinformatics.org.au/tools/altExtron/
AS-ALPS http://as-alps.nagahama-i-bio.ac.jp/index.php
ASpedia http://combio.snu.ac.kr/aspedia/index.html
ASPicDB http://srv00.recas.ba.infn.it/ASPicDB/
BrainRNA-seq https://www.brainrnaseq.org/
DBASS http://www.dbass.org.uk/
FAST DB http://www.genosplice.com/alternative-splicing
FLJ DB http://flj.lifesciencedb.jp/top/
H-DBAS http://www.h-invitational.jp/h-dbas/
HEXEvent http://hexevent.mmg.uci.edu/cgi-bin/HEXEvent/HEXEventWEB.cgi
HOLLYWOOD http://hollywood.mit.edu/hollywood/Login.php
HSF http://www.umd.be/HSF3/index.html
IntSplice https://www.med.nagoya-u.ac.jp/neurogenetics/IntSplice/
MiasDB http://47.88.84.236/Miasdb/index.php
NetGene2 http://www.cbs.dtu.dk/services/NetGene2/
NetUTR http://www.cbs.dtu.dk/services/NetUTR/
SplicePort http://spliceport.cbcb.umd.edu/
SpliceProt http://bioinfoteam.fiocruz.br/spliceprot/index.php
TassDB http://tassdb2.leibniz-fli.de/

Table S2 - Cancer databases

Database URL
arrayMap https://arraymap.org/
CGAProject https://mitelmandatabase.isb-cgc.org/
CancerNet http://bis.zju.edu.cn/CancerNet/
CanGEM http://www.cangem.org/
CanProVar http://canprovar.zhang-lab.org/index.php
CARGO http://cargo2.bioinfo.cnio.es/
CCLE https://portals.broadinstitute.org/ccle
CGMD http://cgmd.in/
ChiTaRS http://chitars.md.biu.ac.il/
COSMIC https://cancer.sanger.ac.uk/cosmic
CPDB https://www.library.ucdavis.edu/database/carcinogenic-potency-database-cpdb/
DBCAT http://dbcat.cgm.ntu.edu.tw/
DbDEMC https://www.picb.ac.cn/dbDEMC/
dbDEPC https://www.scbit.org/dbdepc3/index.php
DiseaseMeth http://bio-bigdata.hrbmu.edu.cn/diseasemeth/
DriverDB http://120.110.158.132:8787/driverdbv2/cancer.php
GEMiCCL https://www.kobic.kr/GEMICCL/
GeneHub-GEPIS http://www.cgl.ucsf.edu/Research/genentech/genehub-gepis/
GSR https://popmodels.cancercontrol.cancer.gov/gsr/
HCMDB http://hcmdb.i-sanger.com/index
HNOCDB http://gyanxet.com/hno.html
ISOexpresso http://wiki.tgilab.org/ISOexpresso/main.php?cat=about
MCF10A https://carcinogenome.org/MCF10A/
MERAV http://merav.wi.mit.edu/
MethmiRbase https://madlab.cpe.ku.ac.th/TR2/?itemID=108747
MGDB http://bioinfo.ahu.edu.cn:8080/Melanoma/
MiRCancer http://mircancer.ecu.edu/
MiTranscript http://mitranscriptome.org/
MSGene http://msgene.bioinfo-minzhao.org/
MTCTScan http://mulinlab.org/mtctscan
NCI ALMANAC https://dtp.cancer.gov/ncialmanac/initializePage.do
NeXtProt https://www.nextprot.org/about/nextprot
OncoDB.HCC http://oncodb.hcc.ibms.sinica.edu.tw/index.htm
OncomiRdbB http://tdb.ccmb.res.in/OncomiRdbB/index.htm
Oncoyeasti http://www.oncoyeasti.org/
Pedican http://pedican.bioinfo-minzhao.org/
Progenetix https://www.progenetix.org/
S-MED https://www.oncomir.umn.edu/SMED/basic_search.php
SelTarbase http://www.seltarbase.org/
TANTIGEN http://projects.met-hilab.org/tadb/
TCGA Portal https://portal.gdc.cancer.gov/
TCRex https://tcrex.biodatamining.be/instructions/
UMDTP53db http://www.umd.be:2072/

Table S3 - Comparative databases

Database URL  
EVOG http://neobio.cs.pusan.ac.kr/evog/  
GALA http://gala.bx.psu.edu/  
GMO http://gametsonline.nwsuaflmz.com/gene%20search.php  
Gene Set http://www.cisreg.ca/gsb/  
HelmCoP http://www.nematode.net/helmcop.html  
Homophila https://www.aminer.cn/pub/53e9bad0b7602d97046fde08/homophila-human-disease-gene-cognates-in-drosophila  
Idiographica http://rtools.cbrc.jp/idiographica/  
IRView http://ir.hgc.jp/  
LMPD http://www.lipidmaps.org/  
MANTEIA http://manteia.igbmc.fr/gene-expression-search.php  
MDWeb http://mmb.irbbarcelona.org/MDWeb2/  
Metab2MeSH http://sartorlab.ccmb.med.umich.edu/node/5  
MGC https://genecollections.nci.nih.gov/MGC/  
Netview http://netview.tigem.it/netview_project/netview_tools.html  
NHPRTR http://nhprtr.org/resources.html  
NRED http://jsm-research.imb.uq.edu.au/NRED  
OpenDOAR http://v2.sherpa.ac.uk/opendoar/  
PhenoHM https://phenome.cchmc.org/phenoBrowser/Phenome  
POMO https://ruoho.uta.fi/wp/pomo/  
POEDB https://giladlab.uchicago.edu/orthoExon/  
RasMol http://www.bernstein-plus-sons.com/software/rasmol/  
ReCGiP http://klab.sjtu.edu.cn/ReCGiP/  
SQUAT http://bsmc.insa-lyon.fr/squat/  
StemMapper http://stemmapper.sysbiolab.eu/  
TiSGeD http://bioinf.xmu.edu.cn:8080/databases/TiSGeD/index.html  
TISSUES https://tissues.jensenlab.org/Search  
ToppCluster https://toppcluster.cchmc.org/  
TBrowser http://tagc.univ-mrs.fr/tbrowser/  
tRFdb http://genome.bioch.virginia.edu/trfdb/  
Vega Browser http://vega.archive.ensembl.org/index.html  
VISTA Browser https://enhancer.lbl.gov/frnt_page_n.shtml  

Table S4 - Disease-specific and variant-disease association

Database URL
GlobinServer http://globin.cse.psu.edu
AutDB http://autism.mindspec.org/autdb/Welcome.do
BioAfrica https://www.krisp.org.za/tools.php
C/VD http://www.padb.org/cvd/index.html
ClinVar https://www.ncbi.nlm.nih.gov/clinvar/
DbDNV http://goods.ibms.sinica.edu.tw/DNVs/
DbGaP https://www.ncbi.nlm.nih.gov/gap/
dbSNP http://www.ncbi.nlm.nih.gov/SNP
DECIPHER https://decipher.sanger.ac.uk/
Denovo-db http://denovo-db.gs.washington.edu/denovo-db/
DGV http://dgv.tcag.ca/
Ageing Atlas http://ageing-map.org/
Diseasome http://www.kobic.kr/diseasome/
DisGeNET https://www.disgenet.org/
DMDM http://bioinf.umbc.edu/dmdm/
EGA https://www.ebi.ac.uk/ega/
GeneReviews https://www.uniprot.org/database/DB-0188
HbVar http://globin.cse.psu.edu/hbvar/menu.html
HGMD http://www.hgmd.cf.ac.uk/ac/index.php
HGSVP https://www.internationalgenome.org/human-genome-structural-variation-consortium/
HGV&TB http://genome.igib.res.in/hgvtb/index.html
HMDD http://www.cuilab.cn/hmdd
HPO https://hpo.jax.org/app/
Hu.MAP http://hu.proteincomplexes.org/
HUMSAVAR https://www.uniprot.org/docs/humsavar
InvFEST http://invfestdb.uab.cat/
IonChannelsdb https://www.nextprot.org/portals/navmut
ITHANET https://www.ithanet.eu/db/ithagenes
Kaviar http://db.systemsbiology.net/kaviar/cgi-pub/Kaviar.pl
KMeyeDB http://mutationview.jp/MutationView/jsp/index.jsp
LaforaDB http://projects.tcag.ca/lafora/
LongevityMap http://genomics.senescence.info/longevity/
LOVD http://www.lovd.nl/
LSDBs https://grenada.lumc.nl/LSDB_list/lsdbs
MARRVEL http://marrvel.org/
MelanomaMine http://melanomamine.bioinfo.cnio.es/
Mutalyzer https://mutalyzer.nl/
MutPred http://mutpred.mutdb.org/
NetChop http://www.cbs.dtu.dk/services/NetChop/
OMIM https://omim.org/
PAHKB https://bioinfo.uth.edu/PAHKB/
PanelApp https://panelapp.genomicsengland.co.uk/
PaPI http://papi.unipv.it/
PharmGKB https://www.pharmgkb.org/
Phenocarta https://gemma.msl.ubc.ca/expressionExperiment/showAllExpressionExperiments.html
PhenoCHF http://www.nactem.ac.uk/PhenoCHF/
PhenoDB https://researchphenodb.net/
PhenoDigm https://www.sanger.ac.uk/science/tools/phenodigm
PhenoHM https://phenome.cchmc.org/phenoBrowser/Phenome
Phenopedia https://phgkb.cdc.gov/PHGKB/startPagePhenoPedia.action
PhenoTips https://phenotips.com/
PhosphOrtho http://www.phosphortholog.com/
PolyPhen2 http://genetics.bwh.harvard.edu/pph2/
PredictSNP2 http://loschmidt.chemi.muni.cz/predictsnp2/
Rat/InterMine http://ratmine.mcw.edu/ratmine/begin.do
RAvariome http://www.h-invitational.jp/hinv/rav/
SNP2TFBS https://ccg.epfl.ch/snp2tfbs/
SNPDelScore https://www.ncbi.nlm.nih.gov/research/snpdelscore/
SNPedia https://www.snpedia.com/
SNPeffect https://snpeffect.switchlab.org/
SNVBox https://karchinlab.org/apps/appSnvBox.html
UGAHash http://ugahash.uni-frankfurt.de/
UMD-Predictor http://umd-predictor.eu/index.php
VarSome https://varsome.com/

Table S5 - Methylation databases

Database URL
ANCOGeneDB https://bioinfo.uth.edu/ancogenedb/
BECon https://redgar598.shinyapps.io/BECon/
DBCAT http://dbcat.cgm.ntu.edu.tw/
DiseaseMeth http://bio-bigdata.hrbmu.edu.cn/diseasemeth/
GED http://gametsepi.nwsuaflmz.com/
Geneimprint http://www.geneimprint.com/site/home
Lnc2Meth http://bio-bigdata.hrbmu.edu.cn/Lnc2Meth/
MethHC http://methhc.mbc.nctu.edu.tw/
PhenoScanner http://www.phenoscanner.medschl.cam.ac.uk/
ROADMAP https://egg2.wustl.edu/roadmap/web_portal/index.html
TCGA https://www.cancer.gov/

Table S6 - Gene expression databases

Database URL
AgeFactDB http://agefactdb.jenage.de/
Allen Brain https://alleninstitute.org/
AllerGAtlas http://biokb.ncpsb.org/AlleRGatlas/
AltExtron http://bioinformatics.org.au/tools/altExtron/
ANGIOGENES http://angiogenes.uni-frankfurt.de/
arrayMap https://arraymap.org/
AS-ALPS http://as-alps.nagahama-i-bio.ac.jp/index.php
ASMBrainBlood https://epigenetics.essex.ac.uk/ASMBrainBlood/
ASpedia http://combio.snu.ac.kr/aspedia/index.html
Cellosaurus https://web.expasy.org/cellosaurus/
CHESS http://ccb.jhu.edu/chess/
Cistrome DB http://dc2.cistrome.org/
Cortecon http://cortecon.neuralsci.org/
CSPA https://wlab.ethz.ch/surfaceome/
CSTEA http://comp-sysbio.org/cstea/
CYCLONET http://cyclonet.biouml.org/
DAnCER http://wodaklab.org/dancer/
DASHR http://dashr2.lisanwanglab.org/
dbCRID http://c1.accurascience.com/dbCRID/
dbOrg https://biodbnet-abcc.ncifcrf.gov/
DisGeNET https://www.disgenet.org/
DRG TXome https://bbs.utdallas.edu/painneurosciencelab/sensoryomics/drgtxome/
EPConDB http://www.cbil.upenn.edu/node/90
ESCAPE http://www.maayanlab.net/ESCAPE/
ESTDAB https://www.ebi.ac.uk/ipd/estdab/
euL1db http://eul1db.ircan.org/
EuroDia http://eurodia.vital-it.ch
ExpEdit https://bioinformatics.cineca.it/expedit/
EdgeExpress https://fantom.gsc.riken.jp/4/edgeexpress/view/#5558263
FARNA https://www.cbrc.kaust.edu.sa/farna/?page=home
FLJ http://flj.lifesciencedb.jp/top/
GEMiCCL https://www.kobic.kr/GEMICCL/
GenAge http://genomics.senescence.info/genes/
Genatlas http://www.genatlas.org/
GeneMicroglia http://shiny.maths.usyd.edu.au/Ellis/MicrogliaPlots
Globin Gene http://globin.cse.psu.edu/
GTEx https://gtexportal.org/home/
HAGR http://genomics.senescence.info/index.php
HCMDB http://hcmdb.i-sanger.com/index
Healthspan http://functional.domains/healthspan/
Hembase http://hembase.niddk.nih.gov
HGDP https://www.hagsc.org/hgdp/
HipSci http://www.hipsci.org/
HIVed http://hivlatency.erc.monash.edu/
hmChIP http://jilab.biostat.jhsph.edu/database/cgi-bin/hmChIP.pl
HoTResDB http://hotresdb.bu.edu/
HPMR http://www.receptome.org/
HPRD http://www.hprd.org/
HSF http://www.umd.be/HSF3/index.html
HuGENavigator https://phgkb.cdc.gov/PHGKB/hNHome.action
Human Erythroblast Maturation https://cellline.molbiol.ox.ac.uk/eryth/cgi-bin/HEM.cgi
IGRhCellID http://igrcid.ibms.sinica.edu.tw/cgi-bin/index.cgi
Inner Ear Transcriptome https://www.tgen.org/patients/neurological-disorders/
Intropolis https://github.com/nellore/intropolis/blob/master/README.md
Islet Regulome Browser http://www.isletregulome.com/isletregulome/
Isobase http://cb.csail.mit.edu/cb/mna/isobase/
ISOexpresso http://wiki.tgilab.org/ISOexpresso/main.php?cat=about
Linc2GO http://www.bioinfo.tsinghua.edu.cn/~liuke/Linc2GO/index.html
Liverbase http://liverbase.hupo.org.cn/index2.jsp
MetaQuery http://metaquery.docpollard.org/
MGEx-Udb http://resource.ibab.ac.in/MGEx-Udb/
MiasDB http://47.88.84.236/Miasdb/index.php
microRNA body https://www.mirnabodymap.org/
MitoAge http://www.mitoage.info/
MSGene http://msgene.bioinfo-minzhao.org/
NHGRI Project https://research.nhgri.nih.gov/microarray/index.shtml
NHPRTR http://nhprtr.org/resources.html
PhenoScanner http://www.phenoscanner.medschl.cam.ac.uk/
Primer Z http://grch37.genepipe.ncgm.sinica.edu.tw/primerz/beginDesign.do
QMEAN https://swissmodel.expasy.org/qmean/
REDIportal http://srv00.recas.ba.infn.it/redidb/index.html
RefEx https://refex.dbcls.jp/index.php?lang=en
RenalDB http://renaldb.uni-frankfurt.de/
Retina http://retina.tigem.it/
RNALocate http://www.rna-society.org/rnalocate/
scRNASeqDB https://bioinfo.uth.edu/scrnaseqdb/
SIEGE http://pulm.bumc.bu.edu/siegeDB
SIGNOR https://signor.uniroma2.it/
SpermBase http://www.spermbase.org/Search.php
The Matrisome http://matrisomeproject.mit.edu/
TiGER http://bioinfo.wilmer.jhu.edu/tiger/
TISSUES https://tissues.jensenlab.org/Search
tRFdb http://genome.bioch.virginia.edu/trfdb/
TRI_tool https://www.vin.bg.ac.rs/180/tools/tfpred.php
TSEM https://hood-price.isbscience.org/research/tsem/
WeGet https://coexpression.cmbi.umcn.nl/

Table S7 - Genomic and sequence databases

Database URL
   
1000Genomes http://www.internationalgenome.org/
3DSNP http://cbportal.org/3dsnp/
3Omics https://3omics.cmdm.tw/
CatalogSTR https://strider.online/
Catalog of enhancers in hESCs http://www.medical-epigenomics.org/papers/barakat2018/
ABS https://www.crg.eu/en/programme/programmes-groups/bioinformatics-and-genomics
AceView http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly
ActiveDriverDB https://github.com/reimandlab/ActiveDriverDB/issues
Adsn http://adsn.ddnetbio.com/
AFND http://www.allelefrequencies.net/
AlloFinder http://mdl.shsmu.edu.cn/ALF/
AMAZONIA http://amazonia.transcriptome.eu/
AmtDB https://amtdb.org/
ANCO-GeneDB https://bioinfo.uth.edu/ancogenedb/
Aneurysm DB http://www.cuilab.cn/agd
AVPpred http://crdd.osdd.net/servers/avppred/
BDO http://bioportal.bioontology.org/ontologies/BDO
BECon https://redgar598.shinyapps.io/BECon/
BioGPS http://biogps.org/
BrainScope https://brainscope.lumc.nl/brainscope
CADD https://cadd.gs.washington.edu/
CCB https://cellcycle.renci.org/
ChIPSummitDB http://summit.med.unideb.hu/summitdb/index.php
Chorogenome https://hicexplorer.usegalaxy.eu/
Cichlids http://cichlids.biosci.gatech.edu/
CITGeneDB http://citgenedb.yubiolab.org
CLIMA http://bioinformatics.hsanmartino.it/clima2/
ClinicalTrials https://clinicaltrials.gov/
ClinVar https://www.ncbi.nlm.nih.gov/clinvar/
ComiR http://www.benoslab.pitt.edu/comir/
CRUNCH http://crunch.unibas.ch/crunch/
cWords http://servers.binf.ku.dk/cwords/
dbDSM http://bioinfo.ahu.edu.cn:8080/dbDSM/index.jsp
dbEMT http://dbemt.bioinfo-minzhao.org/
DBETH <www.hpppi.iicb.res.in/btox/ >
dbMAE https://mae.hms.harvard.edu/
dbNSFP https://sites.google.com/site/jpopgen/dbNSFP
DisGeNET https://www.disgenet.org/
DO https://disease-ontology.org/
Doc2Hpo https://impact2.dbmi.columbia.edu/doc2hpo/
E-RNAi https://www.dkfz.de/signaling/e-rnai3/
EBI https://www.ebi.ac.uk/
eDGAR http://edgar.biocomp.unibo.it/gene_disease_db/index.html
EpiACDev https://cotney.research.uchc.edu/data/
EpimiRBase https://www.epimirbase.eu/
Eponine https://www.sanger.ac.uk/about/who-we-are
ExomeServer https://evs.gs.washington.edu/EVS/
FirstEF http://rulai.cshl.org/tools/FirstEF/
G2Cdb http://www.genes2cognition.org
GENCODE https://www.gencodegenes.org/human/
GenePAtlas http://biocc.hrbmu.edu.cn/GPA/
GeneSetBuildr http://www.cisreg.ca/gsb/
Gene Wiki http://en.wikipedia.org/wiki/Portal:Gene_Wiki
GeneCards
Geneimprint http://www.geneimprint.com/site/home
GeneLoc https://genecards.weizmann.ac.il/geneloc/about_new.shtml
GeneMap <www.ncbi.nlm.nih.gov/genemap>
GUIDES http://guides.sanjanalab.org/#/
H-InvDB http://www.h-invitational.jp/
HADb http://autophagy.lu/index.html
Harmonizome http://amp.pharm.mssm.edu/Harmonizome/
HERVd https://herv.img.cas.cz/
HExpoChem http://www.cbs.dtu.dk/services/HExpoChem-1.0/
HGMD http://www.hgmd.cf.ac.uk/ac/index.php
HGNC https://www.genenames.org
hLGDB http://lysosome.unipg.it/
HMDAD http://www.cuilab.cn/hmdad
HMMER3 https://www.ebi.ac.uk/Tools/hmmer/
HMP https://portal.hmpdacc.org/
HOMD http://www.homd.org
HomzygMapper http://www.homozygositymapper.org/
hORFeome Database http://horfdb.dfci.harvard.edu/
HPO https://hpo.jax.org/app/
HSF http://www.umd.be/HSF3/index.html
HUMA https://huma.rubi.ru.ac.za/
HumCFS https://webs.iiitd.edu.in/raghava/humcfs/index.html
HydPred http://lishuyan.lzu.edu.cn/hydpred/
HyperCLDB http://bioinformatics.hsanmartino.it/hypercldb/
IDADE2 http://bass.uib.es/~jaume/IDADE2/https/index.html
IGSR https://www.internationalgenome.org/1000-genomes-project-publications
iLoc-Cell http://www.jci-bioinfo.cn/iLoc-Hum
IMGT http://www.imgt.org/
integrated gene catalog http://meta.genomics.cn/meta/home
IntSplice https://www.med.nagoya-u.ac.jp/neurogenetics/IntSplice/
InvFEST http://invfestdb.uab.cat/
ITHANET https://www.ithanet.eu/db/ithagenes
Kaviar http://db.systemsbiology.net/kaviar/cgi-pub/Kaviar.pl
lncRNAtor http://lncrnator.ewha.ac.kr/
MAHMI http://mahmi.org/
MARome http://196.1.114.46:8080/MARome/index
MDWeb http://mmb.irbbarcelona.org/MDWeb2/
MEME Suite http://meme-suite.org/
Mendel,MD https://mendelmd.org/
MetaQuery http://metaquery.docpollard.org/
MetaRanker http://www.cbs.dtu.dk/services/MetaRanker/
microDoR http://reprod.njmu.edu.cn/cgi-bin/microdor/index.py
miR2GO http://compbio.uthsc.edu/miR2GO/home.php
mLASSO-Hum http://bioinfo.eie.polyu.edu.hk/mLASSOHumServer/index.html
MSEA https://www.metaboanalyst.ca/
mTCTScan http://mulinlab.org/mtctscan
mtDNA-Serve https://mtdna-server.uibk.ac.at/index.html
Mutalyzer https://mutalyzer.nl/
MutPred http://mutpred.mutdb.org/
NCBI https://www.ncbi.nlm.nih.gov/
NetChop http://www.cbs.dtu.dk/services/NetChop/
NetGene2 http://www.cbs.dtu.dk/services/NetGene2/
NetNGlyc http://www.cbs.dtu.dk/services/NetNGlyc/
Netview http://netview.tigem.it/netview_project/netview_tools.html
NGD http://www.nencki-genomics.org
NHGRI Project https://research.nhgri.nih.gov/microarray/index.shtml
NIF https://neuinfo.org/
OKdb http://okdb.appliedbioinfo.net/
OMIM https://omim.org/
OncoDB.HCC http://oncodb.hcc.ibms.sinica.edu.tw/index.htm
ONTOAD http://bioportal.bioontology.org/ontologies/ONTOAD
OpenTargets https://www.targetvalidation.org/
OrthoDisease http://orthodisease.sbc.su.se/cgi-bin/index.cgi
OsteoporosAtlas http://biokb.ncpsb.org/osteoporosis/index.php
OverGeneDB http://overgenedb.amu.edu.pl
PanelApp https://panelapp.genomicsengland.co.uk/
PaPI http://papi.unipv.it/
PathogenFinder https://cge.cbs.dtu.dk/services/PathogenFinder/
PDID http://biomine.cs.vcu.edu/servers/PDID/index.php
PDZPepInt http://modpepint.informatik.uni-freiburg.de/PDZPepInt/Input.jsp
Pedican http://pedican.bioinfo-minzhao.org/
PepPSy http://peppsy.genouest.org/query
PGP https://www.personalgenomes.org/
PharmGKB https://www.pharmgkb.org/
PhenoHM https://phenome.cchmc.org/phenoBrowser/Phenome
Phenolyzer http://phenolyzer.wglab.org/
PhenomicDB https://en.wikipedia.org/wiki/PhenomicDB
Phenomizer http://compbio.charite.de/phenomizer/
PhenoScanner http://www.phenoscanner.medschl.cam.ac.uk/
PhenoTips https://phenotips.com/
Piphillin http://piphillin.secondgenome.com/
PolyPhen2 http://genetics.bwh.harvard.edu/pph2/
PolySearch2 http://polysearch.cs.ualberta.ca/index
PredictSNP2 http://loschmidt.chemi.muni.cz/predictsnp2/
Progenetix https://www.progenetix.org/
ProteomicsDB https://www.proteomicsdb.org/proteomicsdb/#overview
ProteoRE http://www.proteore.org/
PRS http://mrcieu.mrsoftware.org/PRS_atlas/
PubGene https://www.pubgene.com/
QMEAN https://swissmodel.expasy.org/qmean/
QTRG https://geneticmedicine.weill.cornell.edu/genome
Quokka http://quokka.erc.monash.edu/
R spider http://www.bioprofiling.de/gene_list.html
RAAR http://www.lerner.ccf.org/cancerbio/heemers/RAAR/
RasMol http://www.bernstein-plus-sons.com/software/rasmol/
RatMine https://omictools.com/ratmine-tool
REGene http://regene.bioinfo-minzhao.org/
RIDDLE http://www.functionalnet.org/riddle/
RSSsite https://www.itb.cnr.it/rss/
Saqqaqproject https://ancientgenome.dk/
ScaPD http://bioinfo.wilmer.jhu.edu/ScaPD/
sciAI https://sci.ai/
SEGEL http://www.chengfeng.info/smoking_database.html
Semantic db http://sbb.cellfinder.org/
SNP2TFBS https://ccg.epfl.ch/snp2tfbs/
SNPDelScore https://www.ncbi.nlm.nih.gov/research/snpdelscore/
SNPs GO https://snps-and-go.biocomp.unibo.it/snps-and-go/index.html
SPEED https://speed2.sys-bio.net/
SpindleP http://www.cbs.dtu.dk/services/SpindleP/
StemCellNet http://stemcellnet.sysbiolab.eu/
StSNP http://ilyinlab.org/StSNP/
SubPhosPred http://bioinfo.ncu.edu.cn/SubPhosPred.aspx
SugarBindDB https://sugarbind.expasy.org/
SURFY http://wlab.ethz.ch/surfaceome/
T1Dbase http://www.t1dbase.org
T2D-Db http://t2ddb.ibab.ac.in
TCGA Portal https://www.cancer.gov/
UCSCGenBrowser https://genome.ucsc.edu/cgi-bin/hgGateway
UK10K https://www.uk10k.org/
UMD-Predictor http://umd-predictor.eu/index.php
UniReD http://bioinformatics.med.uoc.gr/unired/
VarSome https://varsome.com/
VDJsolver http://www.cbs.dtu.dk/services/VDJsolver/
Vega http://vega.sanger.ac.uk
Vega Browser http://vega.archive.ensembl.org/index.html
VeryGene http://www.verygene.com
VHLdb http://vhldb.bio.unipd.it/
Zikv-CDB http://zikadb.cpqrr.fiocruz.br

Table S8 - LncRNA and miRNA databases

Database URL
ComiR http://www.benoslab.pitt.edu/comir/
DASHR http://dashr2.lisanwanglab.org/
dbDEMC https://www.picb.ac.cn/dbDEMC/
DES-ncRNA https://www.cbrc.kaust.edu.sa/des_ncrna/
E-RNAi https://www.dkfz.de/signaling/e-rnai3//
exoRBase http://www.exoRBase.org
ExprTargetDB http://www.scandb.org/apps/microrna/
GED http://gametsepi.nwsuaflmz.com/
GenePerturbAtlas http://biocc.hrbmu.edu.cn/GPA/
hLGDB http://lysosome.unipg.it/
HMDD http://www.cuilab.cn/hmdd
HumanViCe http://gyanxet-beta.com/humanvice/
IntmiR https://www.rgcb.res.in/intmir/
IRBase http://mimirna.centenary.org.au/irfinder/database/
Lnc2Meth http://bio-bigdata.hrbmu.edu.cn/Lnc2Meth/
LncATLAS http://lncatlas.crg.eu/
lnCeDB http://gyanxet-beta.com/lncedb/
LNCediting http://bioinfo.life.hust.edu.cn/LNCediting/
LNCipedia https://lncipedia.org/
LncRBase http://bicresources.jcbose.ac.in/zhumur/lncrbase/
lncRNASNP http://bioinfo.life.hust.edu.cn/lncRNASNP#!/
lncRNAtor http://lncrnator.ewha.ac.kr/
LncRNAWiki http://lncrna.big.ac.cn/index.php/Main_Page
lncRNome http://genome.igib.res.in/lncRNome
MethmiRbase https://madlab.cpe.ku.ac.th/TR2/?itemID=108747
microDoR http://reprod.njmu.edu.cn/cgi-bin/microdor/index.py
microRNA.org http://www.microrna.org/
miR-EdiTar http://microrna.osumc.edu/mireditar/
miR2Disease http://www.miR2Disease.org
miR2GO http://compbio.uthsc.edu/miR2GO/home.php
miRCancer http://mircancer.ecu.edu/
miRDB http://mirdb.org/
mirDIP http://ophid.utoronto.ca/mirDIP/
miRGate http://mirgate.bioinfo.cnio.es/miRGate/
miRGen http://carolina.imis.athena-innovation.gr/diana_tools/web/index.php?r=mirgenv3
MirGeneDB https://mirgenedb.org/
miRNA TF loop https://rth.dk/resources/tfmirloop/
miRNAMap http://mirnamap.mbc.nctu.edu.tw/
miRPathDB https://mpd.bioinf.uni-sb.de/
MirSNP http://cmbi.bjmu.edu.cn/mirsnp
miRvar http://genome.igib.res.in/mirlovd
miRWalk http://mirwalk.umm.uni-heidelberg.de/
PITA https://genie.weizmann.ac.il/pubs/mir07/mir07_prediction.html
Polymirts http://compbio.uthsc.edu/miRSNP/
PuTmiR https://www.isical.ac.in/~bioinfo_miu/TF-miRNA/TF-miRNA.html
RenalDB http://renaldb.uni-frankfurt.de/
S-MED https://www.oncomir.umn.edu/SMED/basic_search.php
SlideBase http://slidebase.binf.ku.dk/
The lncRNA Db http://www.valadkhanlab.org/database
TissueAtlas https://ccb-web.cs.uni-saarland.de/tissueatlas/
TriplexRNA https://triplexrna.org/
TUMIR http://www.ncrnalab.com/TUMIR/
Vir-Mir db http://alk.ibms.sinica.edu.tw/cgi-bin/miRNA/miRNA.cgi

Table S9 - Metabolic and enzyme databases

Database URL
1-CMDb http://slsdb.manipal.edu/ocm/
CIDeR http://mips.helmholtz-muenchen.de/cider/
DESTAF https://www.cbrc.kaust.edu.sa/destaf/
dkNET https://dknet.org//
HEMD http://mdl.shsmu.edu.cn/HEMD/
HEPATONET1 http://www.ebi.ac.uk/biomodels-main/MODEL1009150000
HMDB https://hmdb.ca/
HumanCyc https://humancyc.org/
Hupho http://hupho.uniroma2.it/
KinMap http://www.kinhub.org/kinmap/
metabolicMine https://www.humanmine.org/humanmine/begin.do
MSEA https://www.metaboanalyst.ca/
PeroxisomeDB http://www.peroxisomedb.org/
PhosphPred http://phosphopredict.erc.monash.edu/
Piphillin http://piphillin.secondgenome.com/
R spider http://www.bioprofiling.de/gene_list.html
RegenBase http://regenbase.org/
TSEM https://hood-price.isbscience.org/research/tsem/
VMH https://vmh.life/

Table S10 - Proteome and protein-protein interaction databases

Database URL
2D-PAGE http://web.mpiib-berlin.mpg.de/cgi-bin/pdbs/2d-page/extern/index.cgi
AMPAD Portal https://www.synapse.org/#!Synapse:syn2580853/wiki/409840
BioCarta http://www.biocarta.com/
BRD https://brd.nci.nih.gov/brd/
Calcium Gene http://cagedb.uhlenlab.org/
CCInteractome http://interactome.dfci.harvard.edu/
CIDeR http://mips.helmholtz-muenchen.de/cider/
ComPPI https://comppi.linkgroup.hu/
dbDEPC https://www.scbit.org/dbdepc3/index.php
Degradome db http://degradome.uniovi.es/
DenHunt http://proline.biochem.iisc.ernet.in/DenHunt/about_database.php
DEPhOd http://depod.bioss.uni-freiburg.de/
DIIP http://bioinfo.lab.mcgill.ca/resources/diip/
HADb http://autophagy.lu/index.html
HAPPI http://discovery.informatics.uab.edu/HAPPI/
HERVd https://herv.img.cas.cz/
HGPD https://hgpd.lifesciencedb.jp/cgi/
HKUPP http://www.hkupp.org/
HMMER3 https://www.ebi.ac.uk/Tools/hmmer/
HPID http://wilab.inha.ac.kr/hpid/webforms/intro.aspx
HuInteractome http://www.actrec.gov.in/
Human PPI https://gene.sfari.org/
HumProteinpedia http://www.humanproteinpedia.org
HumanNet http://www.functionalnet.org/humannet/about.html
HuPho http://hupho.uniroma2.it/index.php
HuPI https://hupi.ircm.qc.ca/
HuRI http://www.interactome-atlas.org/
HydPred http://lishuyan.lzu.edu.cn/hydpred/
HypoxiaDB http://www.hypoxiadb.com/hypoxiadb.html
iLoc-Cell http://www.jci-bioinfo.cn/iLoc-Hum
Instruct http://instruct.yulab.org/
Integrated Interactions http://dcv.uhnres.utoronto.ca/iid/
InWeb_IM https://www.intomics.com/inbio/map.html#search
KEGG PATHWAY https://www.kegg.jp/
KinMap http://www.kinhub.org/kinmap/
KinoNetworkX http://www.kinasenet.ca/
KLIFS https://klifs.vu-compmedchem.nl/
Labeledln https://ftp.ncbi.nlm.nih.gov/pub/lu/LabeledIn/
Ligandbook https://ligandbook.org
Membranome https://membranome.org/
MiasDB http://47.88.84.236/Miasdb/index.php
MitoP2 http://www.mitop2.de/
mLASSO-Hum http://bioinfo.eie.polyu.edu.hk/mLASSOHumServer/index.html
NetNGlyc http://www.cbs.dtu.dk/services/NetNGlyc/
neXtProt https://www.nextprot.org/about/nextprot
PaPI http://papi.unipv.it/
PCDq http://h-invitational.jp/hinv/pcdq/
PDID http://biomine.cs.vcu.edu/servers/PDID/index.php
PepSweetener https://glycoproteome.expasy.org/pepsweetener/app/
PhosphoPICK http://bioinf.scmb.uq.edu.au/phosphopick/phosphopick
PhosphoPredict http://phosphopredict.erc.monash.edu/
PhosphOrtholog http://www.phosphortholog.com/
PIPs http://www.compbio.dundee.ac.uk/www-pips/index.jsp
PrePPI https://bhapp.c2b2.columbia.edu/PrePPI/index.html
ProKinO http://vulcan.cs.uga.edu/prokino/about/browser
ProteomicsDB https://www.proteomicsdb.org/
Quokka http://quokka.erc.monash.edu/
RasMol http://www.bernstein-plus-sons.com/software/rasmol/
ScaPD http://bioinfo.wilmer.jhu.edu/ScaPD/
SMPDB https://smpdb.ca/view/SMP0000179
SpindleP http://www.cbs.dtu.dk/services/SpindleP/
StSNP http://ilyinlab.org/StSNP/
SubPhosPred http://bioinfo.ncu.edu.cn/SubPhosPred.aspx
SURFY http://wlab.ethz.ch/surfaceome/
The Proteomedb http://proteomebrowser.org/tpb/home.jspx
TissueNet http://netbio.bgu.ac.il/tissuenet/
TRI_tool https://www.vin.bg.ac.rs/180/tools/tfpred.php
UniHI http://www.unihi.org/
VDJsolver http://www.cbs.dtu.dk/services/VDJsolver/

Table S11 - Regulatory databases

Database URL
ChIPSummitDB http://summit.med.unideb.hu/summitdb/index.php
CREME https://creme.dcode.org/
CRUNCH http://crunch.unibas.ch/crunch/
FirstEF http://rulai.cshl.org/tools/FirstEF/
GlycoViewer http://www.glycoviewer.babs.unsw.edu.au/
HERVd https://herv.img.cas.cz/
HumCFS https://webs.iiitd.edu.in/raghava/humcfs/index.html
Interferome http://interferome.its.monash.edu.au/interferome/home.jspx
JASPAR http://jaspar.genereg.net/
MANTA http://manta.cmmt.ubc.ca/manta2/upload
MEME Suite http://meme-suite.org/
MET http://veda.cs.uiuc.edu/MET/
microDoR http://reprod.njmu.edu.cn/cgi-bin/microdor/index.py
OsteosAtlas http://biokb.ncpsb.org/osteoporosis/index.php
PReMod http://genomequebec.mcgill.ca/PReMod
SM-TF http://zoulab.dalton.missouri.edu/SM-TF/
TcoF-DB https://tools.sschmeier.com/tcof/home/
TFBSbank http://tfbsbank.co.uk/
TFClass http://tfclass.bioinf.med.uni-goettingen.de/
TFCONES http://tfcones.fugu-sg.org/
TFM-Explorer https://bioinfo.lifl.fr/TFM/
TMREC http://www.jianglab.cn/TMREC/
TRANSFAC http://genexplain.com/transfac/
TTSMI http://ttsmi.bii.a-star.edu.sg/

Table S12 - Other databases

Database URL
AAgAtlas http://biokb.ncpsb.org/aagatlas/
CytReD http://www.cro-m.eu/CytReD/
dbMHC https://ftp.ncbi.nlm.nih.gov/pub/mhc/mhc/Final%20Archive/
Epipox http://imed.med.ucm.es/epipox/
GADGET http://gadget.biosci.gatech.edu
GDA https://geneticassociationdb.nih.gov/
GIANT https://portals.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium
Global Biobank Engine https://biobankengine.stanford.edu/
GuavaH http://www.guavah.org/
GUIDES http://guides.sanjanalab.org/#/
H2P2 http://h2p2.oit.duke.edu/H2P2Home/
HLA-ADR http://www.allelefrequencies.net/hla-adr/
HLAsupE http://www.immunoinformatics.net/HLAsupE/index.html
HPtaa http://www.bioinfo.org.cn/hptaa/
HyperCLDB http://bioinformatics.hsanmartino.it/hypercldb/
IEDB https://www.iedb.org/
iLoc-Cell http://www.jci-bioinfo.cn/iLoc-Hum
IMGT http://www.imgt.org/
IPD-IMGT/HLA https://www.ebi.ac.uk/ipd/imgt/hla/
IPD-MHC https://www.ebi.ac.uk/ipd/mhc/
LD Hub http://ldsc.broadinstitute.org/
MARome http://196.1.114.46:8080/MARome/index
MetabolomicsGWAS http://metabolomics.helmholtz-muenchen.de/gwas/index.php
MitoAge http://www.mitoage.info/
MNDR http://www.rna-society.org/mndr/
mtDNA-Server https://mtdna-server.uibk.ac.at/index.html
NetMHC-3.0 http://www.cbs.dtu.dk/services/NetMHC/
NetMHCIIpan http://www.cbs.dtu.dk/services/NetMHCIIpan/
PathogenFind https://cge.cbs.dtu.dk/services/PathogenFinder/
PEPVAC http://imed.med.ucm.es/PEPVAC/
PhosphoPICK http://bioinf.scmb.uq.edu.au/phosphopick/phosphopick
PolyDoms https://polydoms.cchmc.org/polydoms/
PolySearch2 http://polysearch.cs.ualberta.ca/index
PRS http://mrcieu.mrsoftware.org/PRS_atlas/
Psmir http://bio-bigdata.hrbmu.edu.cn/Psmir/
ReCGiP http://klab.sjtu.edu.cn/ReCGiP/
SHOGoiN https://stemcellinformatics.org/
SNPDelScore https://www.ncbi.nlm.nih.gov/research/snpdelscore/
StemCellNet http://stemcellnet.sysbiolab.eu/
SWATHAtlas http://www.swathatlas.org/
SysteMHCAtlas https://systemhcatlas.org/
TCLP http://celllines.tron-mainz.de/
TCRex https://tcrex.biodatamining.be/instructions/
The SBT https://ftp.ncbi.nlm.nih.gov/pub/mhc/mhc/Final%20Archive/
VaDE http://bmi-tokai.jp/VaDE/

INTRODUCTION

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https://doi.org/10.1590/1678-4685-gmb-2020-0203